In this Deep Dive session, A/Prof Estelle Verburgh and Dr Kudakwashe Simba discuss the Rapid Access Lymph Node Biopsy Clinic at Groote Schuur hospital as well as the utility of Lymphoma registries. The speakers share their experiences and techniques in handling patient samples, emphasizing the utility of core needle biopsy, the potential of liquid biopsies, and the future of diagnostics in lymphoma.